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蓝瑛（1585-1664），一说（1585-约1666），明代了得画家，字田叔，号蝶叟，晚号石梵衲、猴子、万篆阿主者、西湖研民，又号东郭老农，所居榜额曰“城曲茅堂” ，钱塘（今浙江杭州）东说念主，是浙派后期代表画家之一。

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《溪山秋色图》是一幅绢本设色长卷，纵23.8厘米，横180厘米，现藏于台北故宫博物院。这幅作品创作于1613年，是蓝瑛29岁时仿照元代赵孟和黄公望的笔法绘画的。

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HER2阳性胃癌约占总体胃癌的15%-20%[1]，新型ADC药物T-DXd的出现开启了HER2阳性晚期胃癌的ADC治疗新时代。Ⅱ期DESTINY-Gastric02研究旨在评估T-DXd治疗既往接受过含曲妥珠单抗方案后疾病进展的HER2阳性胃或胃食管交界处腺癌（以下简称胃癌）患者的疗效和安全性。2023年6月14日，该研究全文发表于肿瘤领域顶级期刊《柳叶刀·肿瘤学》（The Lancet Oncology，影响因子54.433）。中位随访10.2个月时，独立中心审查委员会（ICR）评估的客观缓解率（ORR）为42%[2]，进一步验证了T-DXd在HER2阳性晚期胃癌二线治疗的应用价值，有望成为新的二线标准治疗方案。医学界肿瘤频道特邀中南大学湘雅医院曾珊教授回顾梳理HER2阳性晚期胃癌治疗进展，并深入解读DESTINY-Gastric02研究结果，并展望新进展对系统治疗策略的影响。

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在构图上，蓝瑛模仿了元东说念主赵孟的构图形式，以山石和林木为主要元素，通过玄妙的布局和构念念，将画面呈现得填塞而豪阔端倪感。在用笔方面，蓝瑛吸收了黄公望的笔法，以长披麻皴来发扬山石的肌理和质感。在敷色方面，蓝瑛以浅绛色为主调，诓骗素雅的色调将秋天的宁静和崭新发扬得长篇大论。

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通盘这个词画面以右起大片水域为起初，辽远山岭蒙蒙，云气蒸腾。中部山石突起，溪水潺潺迂回从山间流过，坡石上荒芜辞别着树木。近处则是一滑房舍粉饰在千山万水之间，几位文东说念主坐在屋内念书论文，清松舒坦。楼大驾方有瀑水迂迴周折流出，增强了画面的动态感。

蓝瑛诓骗了多数的侧锋皴写来描写山石百度网盘能不能看球赛，使得画面更具有立体感和深度。整幅画水墨填塞，用淡墨淡彩渲染出一片澄明清润的南国初秋高傲，气韵活泼。笔法简通晓利，色调浓淡合适，具透明感。

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